Meridia Information Article:

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Meridia Side Effects... The FDA approved the use of the Meridia diet drug against the wishes of its advisory committee that actually voted against its approval by a 5 to 4 vote. The concern of the committee was that the health risks associated with the use of Meridia for treatment of obesity outweighed the potential benefits.

Since Meridia was first sold in February of 1998, until September 2001, there have been 397 adverse reactions reported to the FDA, including 152 hospitalizations, and 29 deaths. Meridia is under FDA review in response to the petition filed by consumer advocacy group Public Citizen to immediately ban the sales of sibutramine. This action was prompted by the 29 deaths and hundreds of serious Meridia side effects that have been reported. The side effects that Meridia weight loss pills have been associated to are serious and deadly.

In Meridia's patient information it warns patients about pulmonary hypertension (PPH), which is a rare and sometimes fatal disease. PPH causes high blood pressure in the lungs that leads to a feeling of constant breathlessness with minimal exertion, fatigue, dizzy spells, fainting, and chest pain, and there is no known cause of PPH.

Cardiac valve dysfunction, or heart valve disease may also be a Meridia side effect risk. Heart valve disease causes the valves in the heart to allow blood flow backwards through them.

The most common Meridia side effects include, headache, dry mouth, anorexia, constipation, insomnia, increase in blood pressure, increase in heart rate, mental impairments, heart disease, stroke, seizures, and increased sweating. Precautions Before using this drug, tell your doctor your entire medical history, including any allergies (especially drug allergies), liver or kidney disease, high blood pressure or heart disease, history of stroke or seizures, certain eating disorders (e.g., anorexia nervosa), glaucoma (narrow angle), or history of gallstones.

Limit alcohol intake, as it may worsen certain side effects of this medication. It is recommended that women of child-bearing age should use effective birth control while taking this medication. This drug is not recommended for use during pregnancy.

Consult your doctor before using this drug. It is not known whether this drug is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Elderly patients may be more sensitive to the effects of this drug. Use cautiously.

Drug Interactions:
Tell your doctor of all nonprescription and prescription medication you may use, especially other weight reducing agents (e.g., diethylpropion), drugs that can raise blood pressure such as decongestants (e.g., pseudoephedrine, phenylpropanolamine), cough suppressants (e.g., dextromethorphan), antidepressants (e.g., nefazodone, fluoxetine, paroxetine, sertraline, fluvoxamine, venlafaxine), lithium, psychiatric medications (e.g., MAO Inhibitors such as selegiline, moclobemide, furazolidone, phenelzine, tranylcypromine), drugs for migraines (e.g., dihydroergotamine, sumatriptan), tryptophan, certain narcotic pain relievers (e.g., meperidine, pentazocine, fentanyl), ketoconazole, erythromycin, high blood pressure medicine or any drugs which can cause drowsiness, including certain antihistamines (e.g., diphenhydramine), sedatives and anti-seizure drugs.

Antihistamines and decongestants may be found in many nonprescription drugs for cough and cold. Consult your pharmacist. MAO Inhibitors (see above) and this drug should not be taken together. If an MAO Inhibitor or this drug is stopped, wait 2 weeks before starting the other drug.

Med Notes:
Do not share this medication with others. This medication should be used in addition to a reduced calorie diet. Blood pressure and pulse may be measured and laboratory tests performed to monitor side effects.

Missed Dosages:
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double- up" the dose to catch up.

STORAGE: Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture. Keep this and all medications out of the reach of children. Storage Info Store at room temperature away from sunlight and moisture. Keep this and all medications out of the reach of children.

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